GATACA

GATACA is developing novel algorithms and software solutions for virologists. Funded by several Small Business Innovation Research (SBIR) awards from the NSF and NIH (NIAID), their current focus is on the hepatitis B virus (HBV) bioinformatics. They have developed an algorithm for assembling deep coverage NGS data using a novel contig merge-refine-cluster iteration approach for retaining all suspected true variants, resolving haplotypes and characterizing quasispecies. Thir pipeline for the hepatitis C virus (HCV) incorporates resistance profiling and mutation tracking/variant calling algorithms directly from NGS reads.