ZZ BIOTECH
ZZ Biotech LLC is a clinical stage company developing innovative biologic treatments for ischemic stroke. ZZ Biotech was formed in 2006 to focus on the development of 3K3A-APC, a novel second-generation variant of a naturally occurring human protein, activated Protein C (APC). The major unwanted side effect of APC is bleeding, which limits its pharmacologic dosing in man. 3K3A-APC has markedly reduced anticoagulant activity, but preserved cell-protective and anti-inflammatory activities compared... to wild-type APC. In animal models of stroke 3K3A-APC has shown an advantage over wild-type APC in enhanced efficacy and reduced risk for bleeding. Additionally, the combination of 3K3A-APC and tissue Plasminogen Activator (tPA) provides benefits well beyond those found with either agent alone. ZZ Biotech is currently recruiting patients in a multicenter Phase 2 clinical trial of 3K3A-APC in patients suffering from acute ischemic stroke. The study is being supported by the National Institutes of Health through a pair of NeuroNEXT grants. The Phase 2 study is to evaluate safety, tolerability and activity of ZZ Biotechโs 3K3A-APC when given after tissue plasminogen activator (tPA), mechanical thrombectomy, or both, in patients who have experienced moderate to severe ischemic stroke.
ZZ BIOTECH
Social Links:
Industry:
Biotechnology Clinical Trials Therapeutics
Founded:
2006-01-01
Address:
Houston, Texas, United States
Country:
United States
Website Url:
http://www.zzbiotech.com
Total Employee:
1+
Status:
Active
Contact:
(619) 574 0820
Email Addresses:
[email protected]
Total Funding:
7.93 M USD
Technology used in webpage:
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Current Employees Featured
Founder
Acquisitions List
Date | Company | Article | Price |
---|---|---|---|
2016-01-12 | Bioatrix | Bioatrix acquired by ZZ Biotech | N/A |
Investors List
National Institutes of Health
National Institutes of Health investment in Seed Round - ZZ Biotech
Broadview Ventures
Broadview Ventures investment in Seed Round - ZZ Biotech
Official Site Inspections
http://www.zzbiotech.com
- Host name: 77.16.232.35.bc.googleusercontent.com
- IP address: 35.232.16.77
- Location: United States
- Latitude: 38.6583
- Longitude: -77.2481
- Timezone: America/New_York