ZZ BIOTECH

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ZZ Biotech LLC is a clinical stage company developing innovative biologic treatments for ischemic stroke. ZZ Biotech was formed in 2006 to focus on the development of 3K3A-APC, a novel second-generation variant of a naturally occurring human protein, activated Protein C (APC). The major unwanted side effect of APC is bleeding, which limits its pharmacologic dosing in man. 3K3A-APC has markedly reduced anticoagulant activity, but preserved cell-protective and anti-inflammatory activities compared... to wild-type APC. In animal models of stroke 3K3A-APC has shown an advantage over wild-type APC in enhanced efficacy and reduced risk for bleeding. Additionally, the combination of 3K3A-APC and tissue Plasminogen Activator (tPA) provides benefits well beyond those found with either agent alone. ZZ Biotech is currently recruiting patients in a multicenter Phase 2 clinical trial of 3K3A-APC in patients suffering from acute ischemic stroke. The study is being supported by the National Institutes of Health through a pair of NeuroNEXT grants. The Phase 2 study is to evaluate safety, tolerability and activity of ZZ Biotechโ€™s 3K3A-APC when given after tissue plasminogen activator (tPA), mechanical thrombectomy, or both, in patients who have experienced moderate to severe ischemic stroke.

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ZZ BIOTECH

Social Links:

Industry:
Biotechnology Clinical Trials Therapeutics

Founded:
2006-01-01

Address:
Houston, Texas, United States

Country:
United States

Website Url:
http://www.zzbiotech.com

Total Employee:
1+

Status:
Active

Contact:
(619) 574 0820

Email Addresses:
[email protected]

Total Funding:
7.93 M USD

Technology used in webpage:
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Current Employees Featured

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Kent Pryor
Kent Pryor Chief Executive Officer @ ZZ Biotech
Chief Executive Officer
2010-01-01

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Berislav V. Zlokovic
Berislav V. Zlokovic Co-Founder @ ZZ Biotech
Co-Founder

Founder


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Berislav V. Zlokovic

Acquisitions List

Date Company Article Price
2016-01-12 Bioatrix Bioatrix acquired by ZZ Biotech N/A

Investors List

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National Institutes of Health

National Institutes of Health investment in Seed Round - ZZ Biotech

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Broadview Ventures

Broadview Ventures investment in Seed Round - ZZ Biotech

Official Site Inspections

http://www.zzbiotech.com

  • Host name: 77.16.232.35.bc.googleusercontent.com
  • IP address: 35.232.16.77
  • Location: United States
  • Latitude: 38.6583
  • Longitude: -77.2481
  • Timezone: America/New_York

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