RENOVACOR
Renovacor is a preclinical‑stage biopharmaceutical company focused on developing transformative gene therapy‑based treatments for cardiovascular disease. Renovacor’s lead program is a recombinant adeno-associated virus (AAV)‑based gene therapy for patients suffering from dilated cardiomyopathy (DCM) due to mutations in the Bcl2‑associated athanogene 3 (BAG3) gene. Dilated cardiomyopathy is a condition affecting over 3 million patients in the US and growing steadily. Many patients dev... elop DCM due to ischemic heart disease. Recently subpopulations have been identified that develop DCM due to mutations in specific genes that have been shown to result in the development of DCM. One of these specific genes is the BAG3 gene. The prevalence of disease‑causing BAG3 haploinsufficiency is estimated at approximately 35,000 individuals in the United States, representing an orphan disease by FDA guidelines. It is estimated a similar number of DCM patients with BAG3 mutations exist in Europe. These patients are typically younger and progress to end-stage heart failure sooner than patients with ischemic heart disease. Currently, DCM patients with a BAG3 mutation are treated with standard of care for heart failure. Despite improvements in pharmacotherapy and care, the five‑year survival of a patient with DCM is only 50%. The development of a BAG3 gene replacement therapy for patients with DCM that carry BAG3 mutations could potentially prevent the progression of disease in this otherwise healthy population of young adults.
RENOVACOR
Industry:
Biotechnology Health Care Life Science
Founded:
2013-01-01
Address:
Philadelphia, Pennsylvania, United States
Country:
United States
Website Url:
http://www.renovacor.com
Total Employee:
1+
Status:
Active
Contact:
610-424-2650
Email Addresses:
[email protected]
Total Funding:
41 M USD
Technology used in webpage:
SPF Microsoft Exchange Online Amazon Office 365 Mail Microsoft Azure DNS GoDaddy DNS AWS Global Accelerator
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RTW Investments LLC
RTW Investments LLC investment in Post-IPO Equity - Renovacor
683 CAPITAL
683 CAPITAL investment in Post-IPO Equity - Renovacor
Altium Capital
Altium Capital investment in Post-IPO Equity - Renovacor
Longview Ventures
Longview Ventures investment in Post-IPO Equity - Renovacor
Chardan
Chardan investment in Post-IPO Equity - Renovacor
Acorn Bioventures
Acorn Bioventures investment in Post-IPO Equity - Renovacor
Surveyor Capital
Surveyor Capital investment in Post-IPO Equity - Renovacor
Ikarian Capital
Ikarian Capital investment in Post-IPO Equity - Renovacor
Innogest Capital
Innogest Capital investment in Post-IPO Equity - Renovacor
Affinity Asset Advisors
Affinity Asset Advisors investment in Post-IPO Equity - Renovacor
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http://www.renovacor.com Semrush global rank: 3.83 M Semrush visits lastest month: 3.46 K
- Host name: 151.101.66.159
- IP address: 151.101.66.159
- Location: United States
- Latitude: 37.751
- Longitude: -97.822
- Timezone: America/Chicago