GENTEST CORPORATION

GENTEST Corporation is dedicated to the development of novel systems for the in vitro analysis of xenobiotic (drug) metabolism and toxicity. GENTEST scientists are internationally recognized as leaders and innovators in cytochrome P450 cDNA-expression and in vitro xenobiotic techniques. Their demonstrated commitment to research has been rewarded by the receipt of several competitive NIH grants. The results and applications of Their research is reported in peer reviewed journals and at internatio... nal symposia by both GENTEST scientists and Their colleagues/customers in xenobiotic metabolism. GENTEST began operations in 1983, initially focusing on the use of cultured human cells in GLP genotoxicity assays. In 1985, They expanded research activities into the area of xenobiotic metabolism by developing cytochrome P450 cDNA-expression approaches. This led to the first commercial offering of cDNA-expressed human cytochrome P450 enzymes in 1990. Since that time the range of GENTEST products, human cytochrome P450 forms and other xenobiotic-metabolizing enzymes, as well as the specific activity of enzymes in Their products, has increased dramatically.More