CSFREFRESH

CSFRefresh develops a safe and effective treatment for Alzheimer’s disease by improving the removal of AD toxins from the brain. It is developing a novel biomedical device, a patent-pending “smart”, self-regulating cerebrospinal fluid (CSF) shunt capable of improving the CSF circulation. Increasing the CSF turnover rate, the rate at which the CSF volume is replaced each day will clear toxic metabolites from the brain, e.g, amyloid-beta peptide (Aβ) and phospho-tau (pTau) that cause AD. Normal CSF turnover is 4-5 volumes/day. In AD and NPH it is reduced to once/day.