ADDEX THERAPEUTICS
Addex Therapeutics is a clinical-stage pharmaceutical company focused on the development and commercialization of an emerging class of novel orally available small-molecule drugs known as allosteric modulators for neurological disorders. Allosteric modulators offer several potential advantages over conventional non-allosteric molecules and may offer an improved therapeutic approach to conventional "orthosteric" small molecule or biological drugs. Addex's allosteric modulator drug discovery platf... orm targets receptors and other proteins that are recognized as essential for therapeutic intervention. Addex's lead drug candidate, dipraglurant (mGlu5 negative allosteric modulator or NAM), is in a pivotal registration clinical trial for Parkinsonโs disease levodopa induced dyskinesia (PD-LID). Addex is also investigating dipraglurant's therapeutic use in blepharospasm (a type of dystonia), for which a clinical trial is expected to be initiated in Q3 of 2021. Addex's third clinical program, ADX71149 (mGlu2 positive allosteric modulator or PAM), developed in collaboration with Janssen Pharmaceuticals, Inc., is in a Phase 2a proof of concept clinical trial for the treatment of epilepsy. Indivior PLC has licensed Addexโs GABAB PAM program for the development of drug candidates with a focus on addiction. Preclinical programs ongoing with Addex include GABAB PAM for CMT1A, mGlu7 NAM for PTSD, mGlu2 NAM for mild neurocognitive disorders, mGlu4 PAM for Parkinsonโs disease, and mGlu3 PAM for neurodegenerative disorders.
ADDEX THERAPEUTICS
Industry:
Biotechnology Health Care Medical Pharmaceutical
Founded:
2002-01-01
Address:
Plan-les-ouates, Geneve, Switzerland
Country:
Switzerland
Website Url:
http://www.addextherapeutics.com
Total Employee:
11+
Status:
Active
Contact:
+41228841555
Email Addresses:
[email protected]
Total Funding:
189.43 M USD
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Armistice Master Fund LTV
Armistice Master Fund LTV investment in Post-IPO Equity - Addex Therapeutics
Indivior
Indivior investment in Post-IPO Equity - Addex Therapeutics
InnoSuisse
InnoSuisse investment in Grant - Addex Therapeutics
National Institute on Drug Abuse (NIDA)
National Institute on Drug Abuse (NIDA) investment in Grant - Addex Therapeutics
New Enterprise Associates
New Enterprise Associates investment in Post-IPO Equity - Addex Therapeutics
Hercules Bioventure Partners
Hercules Bioventure Partners investment in Post-IPO Equity - Addex Therapeutics
Michael J. Fox Foundation
Michael J. Fox Foundation investment in Grant - Addex Therapeutics
Hercules Bioventure Partners
Hercules Bioventure Partners investment in Post-IPO Equity - Addex Therapeutics
Armistice Capital
Armistice Capital investment in Post-IPO Equity - Addex Therapeutics
Biotechnology Value Fund
Biotechnology Value Fund investment in Post-IPO Equity - Addex Therapeutics
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- IP address: 83.166.152.52
- Location: Switzerland
- Latitude: 47.1449
- Longitude: 8.1551
- Timezone: Europe/Zurich